CRP or not CRP? That Is the Question

CRP or not CRP? That Is the Question

C-reactive protein (CRP) and cardiovascular disease is a very hot topic at present. Excitement and interest have spilled over dramatically from the scientific literature into the media and popular press leading to much speculative comment. However, rigorously controlled and reproducible studies are now laying the basis for a more realistic consensus. The article in this issue of Arteriosclerosi...

Frail or not? That is the question.

coeliac disease: to classify or not to classify – that is the question!

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To scavenge or not to scavenge: that is the question.

Analysis of a series of diffraction data sets measured from four native as well as four nicotinic acid-soaked crystals of trypsin at 100 K shows a high variability in radiation-sensitivity among individual crystals for both nicotinic acid-soaked and native crystals. The level of radiation-sensitivity and the extent of its variability is statistically indistinguishable between the two conditions...

To P or not to P: that is the question.

In 1993 Eugene Harris, a well-known biostatistician at the NIH, wrote an editorial for Clinical Chemistry regarding the use of P values vs confidence intervals in the evaluation of scientific data (1 ). This has long been a contentious topic in the scientific world and one with which each new generation of scientists has had to grapple on the basis of arguments advanced for the use of various s...